(2S)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-methylsulfanyl-butanoic acid
O-Acetyl-L-Serine
CAS: 5147-00-2
Molecular Formula: C5H9NO4
(2S)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-methylsulfanyl-butanoic acid - Names and Identifiers
(2S)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-methylsulfanyl-butanoic acid - Physico-chemical Properties
| Molecular Formula | C5H9NO4 |
| Molar Mass | 147.13 |
| Density | 1.299±0.06 g/cm3(Predicted) |
| Melting Point | 151.5-151.8 °C |
| Boling Point | 297.7±35.0 °C(Predicted) |
| pKa | 1.98±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Use | O-acetylserine (OAS) is a central metabolite of sulfur assimilation, providing the carbon backbone for synthesis of cysteine. Sulfide generated through sulfate reduction is incorporated into OAS to form cysteine. OAS displays a signalling function leading changes in transcript levels of a specific gene set irrespective of the sulfur status of the plant. Treatment with external OAS increases sulfate transporter and adenosine 5′-phosphosulfate reductase gene expression consistent with a model of transcriptional induction by OAS. |
| In vitro study | O-acetylserine (OAS) is a central metabolite of sulfur assimilation, providing the carbon backbone for synthesis of cysteine. Sulfide generated through sulfate reduction is incorporated into OAS to form cysteine. OAS displays a signalling function leading to changes in transcript levels of a specific gene set irrespective of the sulfur status of the plant. Treatment with external OAS increases sulfate transporter and adenosine 5′-phosphosulfate reductase gene expression consistent with a model of transcriptional induction by OAS. |
(2S)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-methylsulfanyl-butanoic acid - Reference
| Reference Show more | 1. [IF=4.429] Hongrui Lv et al."Identification and functional analysis of the mitochondrial cysteine synthase TtCsa2 from Tetrahymena thermophila."J Cell Biochem. 2021 Dec;122(12):1817-1831 |
(2S)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-methylsulfanyl-butanoic acid - Reference Information
| biological activity | O-Acetylserine is an intermediate of cysteine biosynthesis in bacteria and plants. |
| target | Human Endogenous Metabolite |
| in vitro research | O-acetylserine (OAS) is a central metabolite of sulfur assimilation, providing the carbon backbone for synthesis of cysteine. Sulfide generated through sulfate reduction is incorporated into OAS to form cysteine. OAS displays a signalling function leading to changes in transcript levels of a specific gene set irrespective of the sulfur status of the plant. Treatment with external OAS increases sulfate transporter and adenosine 5 '-phosphosulfate reductase gene expression consistent with a model of transcriptional induction by OAS. |
Last Update：2024-04-10 22:29:15
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